A Comparative Analysis of Anemia Prevalence in Renal Failure Patients and Healthy Controls

Sher Wali Khan; Syeeda Madeeha Shah

Authors

Dr Sher Wali Khan Resident Adult Cardiology, Lady Reading Hospital, Peshawar, Pakistan Author https://orcid.org/0009-0000-1481-9787
Dr. Syeeda Madeeha Shah Gynecologist, Khyber Teaching Hospital Peshawar MTI, Peshawar, Pakistan Author

Keywords:

anemia, renal failure, hematological parameters, ferritin levels

Abstract

Background: Anemia is a common complication in patients with renal failure, defined by reduced hemoglobin levels or red blood cell counts.

Objective: This study aimed to provide a comprehensive comparative analysis of anemia in patients with renal failure and healthy persons

Methodology: Fifty participants, including 25 renal failure patients and 25 healthy individuals, were included in this study. Blood samples were collected, and CBCs (CBC) were performed to assess various parameters, including ferritin, mean corpuscular volume (MCV), hemoglobin (Hb), and red blood cell count (RBC). Data was analyzed using SPSS software, employing various statistical tests to compare the two groups.

Results: The study found that 88% of renal failure patients experienced severe anemia, highlighting its higher prevalence in this group. Additionally, 56% of renal failure patients had elevated MCV, aligning with previous research. Furthermore, 36% of renal failure patients exhibited lower ferritin levels, suggesting potential associations between anemia and systemic inflammation

Conclusion: Anemia in renal failure patients is more prevalent and severe, emphasizing the importance of timely intervention to enhance their well-being. Iron supplementation and erythropoiesis-stimulating agents play a pivotal role in managing anemia in this population.